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A comprehensive in silico investigation unravels the structural and functional consequences of non-synonymous single-nucleotide polymorphisms in human OXTR gene

Abstract Background The OXTR gene encodes oxytocin receptor (OXTR), a cell surface protein primarily found in the brain, uterus, and mammary glands. This receptor plays a crucial role in signal transduction by binding with the ligand oxytocin. Various polymorphisms in the OXTR have been linked to ca...

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Principais autores: Puja Mazumder, Shuvo Chandra Das, Sobuj Mondol, Ibrahim Khalil Afif, Mithu Howlader, Shipan Das Gupta, Md. Murad Hossain, Md. Mijanur Rahman
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2025-03-01
Serier:Egyptian Journal of Medical Human Genetics
Fag:
Oxytocin receptor
nsSNPs
Molecular docking
In silico analysis
Polymorphisms
Online adgang:https://doi.org/10.1186/s43042-025-00680-0
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