Prediction of the most deleterious non-synonymous SNPs in the human IL1B gene: evidence from bioinformatics analyses

Abstract Background Polymorphisms in IL1B play a significant role in depression, multiple inflammatory-associated disorders, and susceptibility to infection. Functional non-synonymous SNPs (nsSNPs) result in changes in the encoded amino acids, potentially leading to structural and functional alterat...

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Detalhes bibliográficos

Principais autores:	Ola Abuzaid, Abeer Babiker Idris, Semih Yılmaz, Einass Babikir Idris, Leena Babiker Idris, Mohamed A. Hassan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-06-01
coleção:	BMC Genomic Data
Assuntos:	IL1B nsSNPs Deleterious SNPs Cancer-causing nsSNPs In silico tools
Acesso em linha:	https://doi.org/10.1186/s12863-024-01233-x
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