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Computational and molecular insights on non-synonymous SNPs associated with human RAAS genes: Consequences for Hypertension vulnerability

Hypertension is the foremost modifiable risk factor for cardiovascular and renal diseases, and overall mortality on a global scale. Genetic variants have the potential to alter an individual’s drug responses. In the present study, we employed a comprehensive computational analysis to evaluate the st...

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Principais autores: Jeyanthi Sankar, Beena Briget Kuriakose, Amani Hamad Alhazmi, Ling Shing Wong, Karthikeyan Muthusamy
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-03-01
Serier:Journal of Genetic Engineering and Biotechnology
Fag:
Hypertension
nsSNPs prediction
Drug targets
Human health
Polymorphism
Pharmacogenomics
Online adgang:http://www.sciencedirect.com/science/article/pii/S1687157X25000204
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