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Deficiency of histone lysine methyltransferase SETDB2 in hematopoietic cells promotes vascular inflammation and accelerates atherosclerosis

Epigenetic modifications of the genome, including DNA methylation, histone methylation/acetylation, and noncoding RNAs, have been reported to play a fundamental role in regulating immune response during the progression of atherosclerosis. SETDB2 is a member of the KMT1 family of lysine methyltransfe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xinbo Zhang, Jonathan Sun, Alberto Canfrán-Duque, Binod Aryal, George Tellides, Ying Ju Chang, Yajaira Suárez, Timothy F. Osborne, Carlos Fernández-Hernando
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical investigation 2021-06-01
Saila:JCI Insight
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1172/jci.insight.147984
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