Methyl carnosate, a carnosic acid derivative, attenuates osteoclastogenesis via modulation of RANKL-induced NF-κB activity

Excessive osteoclast activity underlies bone-destructive diseases including osteoporosis and rheumatoid arthritis. RANKL-induced NF-κB signaling represents a critical pathway driving osteoclastogenesis. Here, we report that methyl carnosate, a naturally occurring diterpene from rosemary, inhibits RA...

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Үндсэн зохиолчид:	Lifang Zhang, Chengxu Xie, Xinyi Bao, Mojtaba Tabandeh, Vishwa Deepak
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2026-06-01
Цуврал:	Frontiers in Pharmacology
Нөхцлүүд:	bone resorption methyl carnosate NF-κB osteoclastogenesis RANKL
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1825049/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!