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LGR4 binding small RANKL fragment inhibits RANKL-induced bone resorption

Objective: Owing to the crucial role played by the osteoprotegerin-receptor activator of nuclear factor-kappa B-RANK ligand (OPG-RANK-RANKL) triad in osteoclastogenesis, the interaction among these proteins is an attractive target for developing osteoporosis drugs. RANKL binds to leucine-rich repeat...

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Bibliografische Detailangaben
Hauptverfasser: Y Jang, YJ Cho, Y Ko, H Lee, B Kim, CM Lee, W Lim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Forum Multimedia Publishing LLC 2025-09-01
Schriftenreihe:European Cells & Materials
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Online-Zugang:https://www.ecmjournal.org/papers/vol053/vol053a02.php
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