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Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products

Abstract Tyrosine kinases belong to a family of enzymes that mediate the movement of the phosphate group to tyrosine residues of target protein, thus transmitting signals from the cell surface to cytoplasmic proteins and the nucleus to regulate physiological processes. Non-receptor tyrosine kinases...

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Autors principals: Kodappully S. Siveen, Kirti S. Prabhu, Iman W. Achkar, Shilpa Kuttikrishnan, Sunitha Shyam, Abdul Q. Khan, Maysaloun Merhi, Said Dermime, Shahab Uddin
Format: Artigo
Idioma:Inglês
Publicat: BMC 2018-02-01
Col·lecció:Molecular Cancer
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Accés en línia:http://link.springer.com/article/10.1186/s12943-018-0788-y
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