Acute gastrointestinal graft-versus-host disease is associated with reductions of secondary bile acids following allogeneic hematopoietic cell transplantation

IntroductionAllogeneic hematopoietic cell transplantation (HCT) can cure hematologic malignancies, but 30-70% of recipients experience acute graft-versus-host disease (GvHD). GvHD is associated with perturbations in the gut microbiome. Bile acids are host derived compounds that are transformed by gu...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Robin Cagle, Sean Proll, Samuel S. Minot, Hayley Purcell, Wentao Zhu, Danijel Djukovic, Congzhou Liu, Tina Fiedler, Martha DeMeules, Marco Mielcarek, Sujatha Srinivasan, Daniel Raftery, Michael Wu, Steven A. Pergam, David N. Fredricks
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Frontiers Media S.A. 2026-07-01
سلاسل:	Frontiers in Microbiology
الموضوعات:	bai operon bile acid metabolism bile salt hydrolase graft-versus-host disease gut microbiome hematopoietic cell transplant
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fmicb.2026.1818647/full
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!