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Dynamic Interplay of Innate and Adaptive Immunity During Sterile Retinal Inflammation: Insights From the Transcriptome

The pathogenesis of many retinal degenerations, such as age-related macular degeneration (AMD), is punctuated by an ill-defined network of sterile inflammatory responses. The delineation of innate and adaptive immune milieu among the broad leukocyte infiltrate, and the gene networks, which construct...

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Principais autores: Riccardo Natoli, Elizabeth Mason, Haihan Jiao, Aaron Chuah, Hardip Patel, Nilisha Fernando, Krisztina Valter, Christine A. Wells, Jan Provis, Matt Rutar
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-07-01
Serier:Frontiers in Immunology
Fag:
retinal diseases
macular degeneration
neuroinflammation
sterile inflammation
leukocytes recruitment
complement system proteins
Online adgang:https://www.frontiersin.org/article/10.3389/fimmu.2018.01666/full
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