Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration

Abstract Background Chemokine signalling is required for the homing of leukocytes during retinal inflammation, and is associated with pathogenesis of diseases such as age-related macular degeneration (AMD). Here, we explore the role of interleukin-1β (IL-1β) in modulating AMD-associated chemokines C...

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書誌詳細

主要な著者:	Riccardo Natoli, Nilisha Fernando, Michele Madigan, Joshua A. Chu-Tan, Krisztina Valter, Jan Provis, Matt Rutar
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2017-04-01
シリーズ:	Molecular Neurodegeneration
主題:	Retinal degeneration Microglia Interleukin-1β IL-1β Chemokines RPE
オンライン･アクセス:	http://link.springer.com/article/10.1186/s13024-017-0175-y
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