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mAb production kinetics in CHO batch culture: exploring extracellular and intracellular dynamics

Monoclonal antibodies (mAbs) are complex therapeutic proteins commonly produced by Chinese Hamster Ovary cell culture. Cells are cultivated using a chemically defined medium containing essential nutrients like glucose, amino acids, vitamins, etc., that cells use to grow and produce the target protei...

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Principais autores: Alejandro Avilan Garzon, Bruno Ebel, Cédric Paris, Samuel Schneider, David Pfister, Eric Olmos
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2025-05-01
Serija:Frontiers in Bioengineering and Biotechnology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1546105/full
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