Código QR (código de barras bidimensional)

The Temozolomide Mutational Signature: Mechanisms, Clinical Implications, and Therapeutic Opportunities in Primary Brain Tumor Management

Temozolomide (TMZ) remains foundational in the management of adult-type diffuse gliomas in general, and glioblastoma specifically. However, its efficacy harbors an evolutionary trade-off. TMZ drives its cytotoxicity through generating O<sup>6</sup>-methylguanine lesions, especially active in MGMT-si...

ver descrição completa

Na minha lista:
Principais autores: Adar Yaacov, Roni Gillis, Jaber Salim, Daniela Katz, Noam Asna, Iddo Paldor, Albert Grinshpun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-12-01
coleção:Cells
Assuntos:
glioma
Temozolomide
mutational signatures
personalized medicine
Acesso em linha:https://www.mdpi.com/2073-4409/15/1/57
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados