Gentianella acuta-derived Gen-miR-5 regulates HDAC6 lactylation by targeting PFKP/YAP/p300 axis to attenuate cardiac hypertrophy

Impairment of cardiomyocyte mitochondrial function caused by pressure overload is a central event in the development of cardiac hypertrophy (CH). Gentianella acuta Hulten, widely consumed as an herbal tea alternative by the Mongolian and Ewenki hunters, has demonstrated significant protective effect...

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Principais autores:	Hongyao Ge, Jiahuan Sun, Zhenyu Du, Weizhe Liu, Cheng Dai, Yu Zhang, Yu Liu, Gaoshan Yang, Aiying Li
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Tsinghua University Press 2026-03-01
סדרה:	Food Science and Human Wellness
נושאים:	gentianella acuta-derived mirnas cardiac hypertrophy platelet isoform phosphofructokinase hdac6 lactylation mitochondrial homeostasis
גישה מקוונת:	https://www.sciopen.com/article/10.26599/FSHW.2024.9250399
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