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PFKP is required for chemoresistant phenotype of breast cancer through modulating the formation of CD133+ cancer stem like cells

Abstract Breast cancer is the foremost cause of cancer-related death in women globally, and taxane-anthracycline (TA) combination regimens represent standard frontline chemotherapy. Although widely administered, the pathological complete response rate to TA therapy is less than 30%, and chemoresista...

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Autores principales: Kai Fang, Yue Ma, Lihua Li, Yan Yue, Hang Ruan, Sidong Xiong
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer 2026-04-01
Colección:Molecular Biomedicine
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Acceso en línea:https://doi.org/10.1186/s43556-026-00454-z
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