Dynamic Phosphorylation of G9a Regulates its Repressive Activity on Chromatin Accessibility and Mitotic Progression

Abstract Phosphorylation of Ser10 of histone H3 (H3S10p), together with the adjacent methylation of Lys9 (H3K9me), has been proposed to function as a ‘phospho‐methyl switch’ to regulate mitotic chromatin architecture. Despite of immense understanding of the roles of H3S10 phosphorylation, how H3K9me...

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Detalhes bibliográficos

Principais autores:	Qizhi Geng, Yue‐Yu Kong, Weizhe Li, Jianhao Zhang, Haoli Ma, Yuhang Zhang, Lin‐Tai Da, Yan Zhao, Hai‐Ning Du
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2023-10-01
coleção:	Advanced Science
Assuntos:	chromatin accessibility G9a phosphorylation mitotic progression Plk1, PPP2CB
Acesso em linha:	https://doi.org/10.1002/advs.202303224
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