Dynamic Phosphorylation of G9a Regulates its Repressive Activity on Chromatin Accessibility and Mitotic Progression

Abstract Phosphorylation of Ser10 of histone H3 (H3S10p), together with the adjacent methylation of Lys9 (H3K9me), has been proposed to function as a ‘phospho‐methyl switch’ to regulate mitotic chromatin architecture. Despite of immense understanding of the roles of H3S10 phosphorylation, how H3K9me...

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Bibliografske podrobnosti

Principais autores:	Qizhi Geng, Yue‐Yu Kong, Weizhe Li, Jianhao Zhang, Haoli Ma, Yuhang Zhang, Lin‐Tai Da, Yan Zhao, Hai‐Ning Du
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2023-10-01
Serija:	Advanced Science
Teme:	chromatin accessibility G9a phosphorylation mitotic progression Plk1, PPP2CB
Online dostop:	https://doi.org/10.1002/advs.202303224
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