Metabolic Detoxification of Glucose and 4-Hydroxynonenal in Human Neuroblastoma Cell Models
Background: Neuroblastoma (NB) progression is influenced by metabolic and redox adaptations. The polyol pathway, driven by aldose reductase (AKR1B1) and sorbitol dehydrogenase (SORD), is activated in hyperglycemic conditions, while detoxification of lipid peroxidation products such as 4-hydroxynonen...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2026-02-01
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| coleção: | Antioxidants |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/2076-3921/15/3/298 |
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