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Can probiotics be an alternative to chlorhexidine for oral care in the mechanically ventilated patient? A multicentre, prospective, randomised controlled open trial

Abstract Background Pathogenic enteric bacteria aspirated from the oropharynx are the main cause of ventilator-associated pneumonia (VAP). Using chlorhexidine (CHX) orally or selective decontamination has been shown to reduce VAP. In a pilot study we found that oral care with the probiotic bacterium...

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Principais autores: Bengt Klarin, Anne Adolfsson, Anders Torstensson, Anders Larsson
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-10-01
Serier:Critical Care
Fag:
Oral care
Mechanically ventilated patients
Probiotics
Lactobacillus plantarum 299
Chlorhexidine
Resistance to antibiotics
Online adgang:http://link.springer.com/article/10.1186/s13054-018-2209-4
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