Development of Novel Fluorinated Polyphenols as Selective Inhibitors of DYRK1A/B Kinase for Treatment of Neuroinflammatory Diseases including Parkinson’s Disease
Natural polyphenol derivatives such as those found in green tea have been known for a long time for their useful therapeutic activity. Starting from EGCG, we have discovered a new fluorinated polyphenol derivative (<b>1c</b>) characterized by improved inhibitory activity against DYRK1A/B enzymes and...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
MDPI AG
2023-03-01
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| Sarja: | Pharmaceuticals |
| Aiheet: | |
| Linkit: | https://www.mdpi.com/1424-8247/16/3/443 |
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