Development of Novel Fluorinated Polyphenols as Selective Inhibitors of DYRK1A/B Kinase for Treatment of Neuroinflammatory Diseases including Parkinson’s Disease
Natural polyphenol derivatives such as those found in green tea have been known for a long time for their useful therapeutic activity. Starting from EGCG, we have discovered a new fluorinated polyphenol derivative (<b>1c</b>) characterized by improved inhibitory activity against DYRK1A/B enzymes and...
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| Автори: | , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
MDPI AG
2023-03-01
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| Серія: | Pharmaceuticals |
| Предмети: | |
| Онлайн доступ: | https://www.mdpi.com/1424-8247/16/3/443 |
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