Pan‐Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival

Abstract Genetic alterations in cancer cells trigger oncogenic transformation, a process largely mediated by the dysregulation of kinase and transcription factor (TF) activities. While the mutational profiles of thousands of tumours have been extensively characterised, the measurements of protein ac...

Description complète

Détails bibliographiques

Auteurs principaux:	Abel Sousa, Aurelien Dugourd, Danish Memon, Borgthor Petursson, Evangelia Petsalaki, Julio Saez‐Rodriguez, Pedro Beltrao
Format:	Artigo
Langue:	Inglês
Publié:	Springer Nature 2023-01-01
Collection:	Molecular Systems Biology
Sujets:	adaptation cancer genomics cell signalling phosphoproteomics protein activities
Accès en ligne:	https://doi.org/10.15252/msb.202110631
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!