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Rod pathway and cone pathway retinal dysfunction in the 5xFAD mouse model of Alzheimer’s disease

Abstract To characterize rod- and cone-pathway function in the 5xFAD mouse model of Alzheimer’s disease (AD) using the full-field electroretinogram (ERG). Dark-adapted (DA; rod-pathway) and light-adapted (LA; cone-pathway) ERGs were recorded from three-month-old 5xFAD and wild type (WT) mice. ERGs w...

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Autors principals: J. Jason McAnany, Nathanael Matei, Yi-Fan Chen, Karen Liu, Jason C. Park, Mahnaz Shahidi
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2021-03-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-021-84318-2
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