Combination decoction of Astragalus mongholicus and Salvia miltiorrhiza mitigates pressure-overload cardiac dysfunction by inhibiting multiple ferroptosis pathways

BackgroundAstragalus mongholicus (AM) and Salvia miltiorrhiza (SM) are commonly used in traditional Chinese medicine to treat heart failure (HF). Ferroptosis has been studied as a key factor in the occurrence of HF. It remains unclear whether the combined use of AM and SM can effectively improve HF...

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Autors principals:	Qiyao Xu, Xuan Liu, Zhaoyang Chen, Can Guo, Pengyu Lu, Sujie Zhang, Xindong Wang, Jianping Shen
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-12-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	ferroptosis heart failure Astragalus mongholicus Salvia miltiorrhiza GPX4 FSP1
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1447546/full
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