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Combination decoction of Astragalus mongholicus and Salvia miltiorrhiza mitigates pressure-overload cardiac dysfunction by inhibiting multiple ferroptosis pathways

BackgroundAstragalus mongholicus (AM) and Salvia miltiorrhiza (SM) are commonly used in traditional Chinese medicine to treat heart failure (HF). Ferroptosis has been studied as a key factor in the occurrence of HF. It remains unclear whether the combined use of AM and SM can effectively improve HF...

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Furkejuvvon:
Váldodahkkit: Qiyao Xu, Xuan Liu, Zhaoyang Chen, Can Guo, Pengyu Lu, Sujie Zhang, Xindong Wang, Jianping Shen
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2024-12-01
Ráidu:Frontiers in Pharmacology
Fáttát:
ferroptosis
heart failure
Astragalus mongholicus
Salvia miltiorrhiza
GPX4
FSP1
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fphar.2024.1447546/full
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