The effect of montelukast, a leukotriene receptor antagonist, on the acetic acid-induced model of colitis in rats: Involvement of NO-cGMP-KATP channels pathway

Inflammatory bowel disease is a chronic autoimmune disorder that may involve entire gastrointestinal tract. The leukotrienes have a role as mediators in the pathophysiology of colitis. Here, we investigated the effect of a leukotriene receptor antagonist, montelukast, and also the role of the NO-cGM...

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Hlavní autoři:	Behnam Ghorbanzadeh, Mohammad Amin Behmanesh, Roya Mahmoudinejad, Mehdi Zamaniyan, Shadi Ekhtiar, Yousef Paridar
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-09-01
Edice:	Frontiers in Pharmacology
Témata:	montelucast nitric oxide cGMP cyclic guanosine monophosphate KATP channels rats
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1011141/full
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