Metformin Ameliorates Lipopolysaccharide-Induced Depressive-Like Behaviors and Abnormal Glutamatergic Transmission

Metformin, a first-line drug for type 2 diabetes mellitus (T2DM), has been found to reduce depressive symptoms in patients with comorbid depression and other diseases. However, it is largely unclear how metformin ameliorates depressive-like behaviors. Here, we used lipopolysaccharide (LPS) to induce...

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Autors principals:	Jiang Chen, Tian Zhou, A-Min Guo, Wen-Bing Chen, Dong Lin, Zi-Yang Liu, Er-Kang Fei
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2020-10-01
Col·lecció:	Biology
Matèries:	depression metformin lipopolysaccharide (LPS) synaptic transmission
Accés en línia:	https://www.mdpi.com/2079-7737/9/11/359
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