NfL concentration in CSF is a quantitative marker of the rate of neurodegeneration in aging and Huntington's disease: a semi-mechanistic model-based analysis

The concentrations of neurofilament light chain (NfL) in cerebrospinal fluid (CSF) and plasma have become key biomarkers of many neurodegenerative diseases, including Huntington's Disease (HD). However, the relationship between the dynamics of NfL concentrations in CSF and the time-course of neurode...

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Autors principals:	Matthias Machacek, Elena Garcia-Montoya, Peter McColgan, Patricia Sanwald-Ducray, Norman Alan Mazer
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-07-01
Col·lecció:	Frontiers in Neuroscience
Matèries:	neurodegeneration atrophy Huntington's disease neurofilament light chain cerebrospinal fluid mathematical
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fnins.2024.1420198/full
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