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SETDB1 interactions with PELP1 contributes to breast cancer endocrine therapy resistance

Abstract Background Methyltransferase SETDB1 is highly expressed in breast cancer (BC), however, the mechanisms by which SETDB1 promotes BC progression to endocrine therapy resistance remains elusive. In this study, we examined the mechanisms by which SETDB1 contribute to BC endocrine therapy resist...

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Автори: Zexuan Liu, Junhao Liu, Behnam Ebrahimi, Uday P. Pratap, Yi He, Kristin A. Altwegg, Weiwei Tang, Xiaonan Li, Zhao Lai, Yidong Chen, Liangfang Shen, Gangadhara R. Sareddy, Suryavathi Viswanadhapalli, Rajeshwar R. Tekmal, Manjeet K. Rao, Ratna K. Vadlamudi
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2022-04-01
Серія:Breast Cancer Research
Предмети:
SETDB1
Akt
PELP1
Breast cancer
Therapy resistance
Онлайн доступ:https://doi.org/10.1186/s13058-022-01520-4
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