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SETDB1 interactions with PELP1 contributes to breast cancer endocrine therapy resistance

Abstract Background Methyltransferase SETDB1 is highly expressed in breast cancer (BC), however, the mechanisms by which SETDB1 promotes BC progression to endocrine therapy resistance remains elusive. In this study, we examined the mechanisms by which SETDB1 contribute to BC endocrine therapy resist...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Zexuan Liu, Junhao Liu, Behnam Ebrahimi, Uday P. Pratap, Yi He, Kristin A. Altwegg, Weiwei Tang, Xiaonan Li, Zhao Lai, Yidong Chen, Liangfang Shen, Gangadhara R. Sareddy, Suryavathi Viswanadhapalli, Rajeshwar R. Tekmal, Manjeet K. Rao, Ratna K. Vadlamudi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-04-01
Schriftenreihe:Breast Cancer Research
Schlagworte:
SETDB1
Akt
PELP1
Breast cancer
Therapy resistance
Online-Zugang:https://doi.org/10.1186/s13058-022-01520-4
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