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Exploration of the main sites for the transformation of normal prion protein (PrPC) into pathogenic prion protein (PrPsc)

Introduction: The functions and mechanisms of prion proteins (PrPC) are currently unknown, but most experts believe that deformed or pathogenic prion proteins (PrPSc) originate from PrPC, and that there may be plural main sites for the conversion of normal PrPC into PrPSc. In order to better underst...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Liu Xi-Lin, Feng Xiao-Li, Wang Guang-Ming, Gong Bin-Bin, Ahmad Waqas, Liu Nan-Nan, Zhang Yuan-Yuan, Yang Li, Ren Hong-Lin, Cui Shu-Sen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Sciendo 2017-03-01
Schriftenreihe:Journal of Veterinary Research
Schlagworte:
mice
brain
prion proteins
myelin sheath
particle aggregation
Online-Zugang:https://doi.org/10.1515/jvetres-2017-0002
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