Construction and characterization of novel Mycobacterium tuberculosis-derived triple and quadruple knockout vaccines against tuberculosis

ABSTRACT Tuberculosis (TB) is a deadly disease that claims the lives of over a million people each year worldwide. The Bacille Calmette-Guérin vaccine has long been used to protect against TB, but it produces variable effects across different populations and fails to protect against adult pulmonary...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Omar Garnica, Raja Veerapandian, Kishore Das, Abhishek Mishra, Varsha Rawat, Areanna Carmona, Vivek Chauhan, Rakesh Kumar, Jessica Chacon, Arshad Khan, Enrique I. Ramos, Shrikanth S. Gadad, Chinnaswamy Jagannath, Subramanian Dhandayuthapani
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	American Society for Microbiology 2026-05-01
Rangatū:	Infection and Immunity
Ngā marau:	tuberculosis Mycobacterium tuberculosis gene deletion attenuated live vaccines immunogenicity protection
Urunga tuihono:	https://journals.asm.org/doi/10.1128/iai.00500-25
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!