Construction and characterization of novel Mycobacterium tuberculosis-derived triple and quadruple knockout vaccines against tuberculosis

ABSTRACT Tuberculosis (TB) is a deadly disease that claims the lives of over a million people each year worldwide. The Bacille Calmette-Guérin vaccine has long been used to protect against TB, but it produces variable effects across different populations and fails to protect against adult pulmonary...

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Detalhes bibliográficos

Principais autores:	Omar Garnica, Raja Veerapandian, Kishore Das, Abhishek Mishra, Varsha Rawat, Areanna Carmona, Vivek Chauhan, Rakesh Kumar, Jessica Chacon, Arshad Khan, Enrique I. Ramos, Shrikanth S. Gadad, Chinnaswamy Jagannath, Subramanian Dhandayuthapani
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2026-05-01
coleção:	Infection and Immunity
Assuntos:	tuberculosis Mycobacterium tuberculosis gene deletion attenuated live vaccines immunogenicity protection
Acesso em linha:	https://journals.asm.org/doi/10.1128/iai.00500-25
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