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Construction and characterization of novel Mycobacterium tuberculosis-derived triple and quadruple knockout vaccines against tuberculosis

ABSTRACT Tuberculosis (TB) is a deadly disease that claims the lives of over a million people each year worldwide. The Bacille Calmette-Guérin vaccine has long been used to protect against TB, but it produces variable effects across different populations and fails to protect against adult pulmonary...

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Wedi'i Gadw mewn:
Prif Awduron: Omar Garnica, Raja Veerapandian, Kishore Das, Abhishek Mishra, Varsha Rawat, Areanna Carmona, Vivek Chauhan, Rakesh Kumar, Jessica Chacon, Arshad Khan, Enrique I. Ramos, Shrikanth S. Gadad, Chinnaswamy Jagannath, Subramanian Dhandayuthapani
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2026-05-01
Cyfres:Infection and Immunity
Pynciau:
tuberculosis
Mycobacterium tuberculosis
gene deletion
attenuated live vaccines
immunogenicity
protection
Mynediad Ar-lein:https://journals.asm.org/doi/10.1128/iai.00500-25
Tagiau: Ychwanegu Tag
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