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Stochastic model of vesicular stomatitis virus replication reveals mutational effects on virion production.

We present the first complete stochastic model of vesicular stomatitis virus (VSV) intracellular replication. Previous models developed to capture VSV's intracellular replication have either been ODE-based or have not represented the complete replicative cycle, limiting our ability to understand the...

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Bibliografiske detaljer
Principais autores: Connor R King, Casey-Tyler Berezin, Jean Peccoud
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2024-02-01
Serier:PLoS Computational Biology
Online adgang:https://doi.org/10.1371/journal.pcbi.1011373
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