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Stochastic model of vesicular stomatitis virus replication reveals mutational effects on virion production.

We present the first complete stochastic model of vesicular stomatitis virus (VSV) intracellular replication. Previous models developed to capture VSV's intracellular replication have either been ODE-based or have not represented the complete replicative cycle, limiting our ability to understand the...

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Autori principali: Connor R King, Casey-Tyler Berezin, Jean Peccoud
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2024-02-01
Serie:PLoS Computational Biology
Accesso online:https://doi.org/10.1371/journal.pcbi.1011373
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