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Cryptococcus neoformans Δsgl1 Vaccination Requires Either CD4+ or CD8+ T Cells for Complete Host Protection

Cryptococcus neoformans is a fungal pathogen causing life-threatening meningoencephalitis in susceptible individuals. Fungal vaccine development has been hampered by the fact that cryptococcosis occurs during immunodeficiency. We previously reported that a C. neoformans mutant (Δsgl1) accumulating s...

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Auteurs principaux: Tyler G. Normile, Antonella Rella, Maurizio Del Poeta
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021-09-01
Collection:Frontiers in Cellular and Infection Microbiology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fcimb.2021.739027/full
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