Cryptococcus neoformans Δsgl1 Vaccination Requires Either CD4+ or CD8+ T Cells for Complete Host Protection

Cryptococcus neoformans is a fungal pathogen causing life-threatening meningoencephalitis in susceptible individuals. Fungal vaccine development has been hampered by the fact that cryptococcosis occurs during immunodeficiency. We previously reported that a C. neoformans mutant (Δsgl1) accumulating s...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Tyler G. Normile, Antonella Rella, Maurizio Del Poeta
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-09-01
Schriftenreihe:	Frontiers in Cellular and Infection Microbiology
Schlagworte:	Cryptococcus neoformans cryptococcosis host immune response immunodeficiency vaccination sterylglucosides
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fcimb.2021.739027/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!