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Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system

Background: Neuroinflammation is involved in the pathophysiology of Alzheimer's disease (AD), including immune-linked genetic variants and molecular pathways, microglia and astrocytes. Multiple Sclerosis (MS) is a chronic, immune-mediated disease with genetic and environmental risk factors and neuro...

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Principais autores: Vera Fominykh, Alexey A. Shadrin, Piotr P. Jaholkowski, Shahram Bahrami, Lavinia Athanasiu, Douglas P. Wightman, Emil Uffelmann, Danielle Posthuma, Geir Selbæk, Anders M. Dale, Srdjan Djurovic, Oleksandr Frei, Ole A. Andreassen
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-07-01
Serier:Neurobiology of Disease
Fag:
Alzheimer's disease
Multiple sclerosis
Genetic overlap
Pleiotropy
Dementia
Neurodegeneration
Online adgang:http://www.sciencedirect.com/science/article/pii/S0969996123001894
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