Cytosolic DNA inhibits rDNA transcription by retaining the RNA polymerase I transcription machinery
Abstract Cytosolic DNA, derived from cellular damage or microbial infection, functions as a pivotal trigger for the host innate immune responses by activating intracellular DNA-sensing machinery, including the cGAS-STING pathway. However, whether cytosolic DNA is involved in DNA-sensing pathway-inde...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Nature
2026-05-01
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| coleção: | The EMBO Journal |
| Acesso em linha: | https://doi.org/10.1038/s44318-026-00792-2 |
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