The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors.
A somatic mutation in the FOXL2 gene is reported to be present in almost all (97%; 86/89) morphologically defined, adult-type, granulosa-cell tumors (A-GCTs). This FOXL2 c.402C>G mutation changes a highly conserved cysteine residue to a tryptophan (p.C134W). It was also found in a minority of other...
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| Huvudupphov: | , , , , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Public Library of Science (PLoS)
2009-11-01
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| Serie: | PLoS ONE |
| Länkar: | http://europepmc.org/articles/PMC2777318?pdf=render |
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