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Functional exploration of the adult ovarian granulosa cell tumor-associated somatic FOXL2 mutation p.Cys134Trp (c.402C>G).

<h4>Background</h4>The somatic mutation in the FOXL2 gene c.402C>G (p.Cys134Trp) has recently been identified in the vast majority of adult ovarian granulosa cell tumors (OGCTs) studied. In addition, this mutation seems to be specific to adult OGCTs and is likely to be a driver of malignant transfor...

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Autors principals: Bérénice A Benayoun, Sandrine Caburet, Aurélie Dipietromaria, Adrien Georges, Barbara D'Haene, P J Eswari Pandaranayaka, David L'Hôte, Anne-Laure Todeschini, Sankaran Krishnaswamy, Marc Fellous, Elfride De Baere, Reiner A Veitia
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2010-01-01
Col·lecció:PLoS ONE
Accés en línia:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20098707/?tool=EBI
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