NUP98 and RAE1 sustain progenitor function through HDAC-dependent chromatin targeting to escape from nucleolar localization

Abstract Self-renewing somatic tissues rely on progenitors to support the continuous tissue regeneration. The gene regulatory network maintaining progenitor function remains incompletely understood. Here we show that NUP98 and RAE1 are highly expressed in epidermal progenitors, forming a separate co...

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Bibliografische Detailangaben

Hauptverfasser:	Amy E. Neely, Laura A. Blumensaadt, Patric J. Ho, Sarah M. Lloyd, Junghun Kweon, Ziyou Ren, Xiaomin Bao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2023-06-01
Schriftenreihe:	Communications Biology
Online-Zugang:	https://doi.org/10.1038/s42003-023-05043-2
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