NUP98 and RAE1 sustain progenitor function through HDAC-dependent chromatin targeting to escape from nucleolar localization

Abstract Self-renewing somatic tissues rely on progenitors to support the continuous tissue regeneration. The gene regulatory network maintaining progenitor function remains incompletely understood. Here we show that NUP98 and RAE1 are highly expressed in epidermal progenitors, forming a separate co...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Amy E. Neely, Laura A. Blumensaadt, Patric J. Ho, Sarah M. Lloyd, Junghun Kweon, Ziyou Ren, Xiaomin Bao
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2023-06-01
Цуврал:	Communications Biology
Онлайн хандалт:	https://doi.org/10.1038/s42003-023-05043-2
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!