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8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineage.

Ten years on from the finishing of the human reference genome sequence, it remains unclear what fraction of the human genome confers function, where this sequence resides, and how much is shared with other mammalian species. When addressing these questions, functional sequence has often been equated...

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Detalhes bibliográficos
Main Authors: Chris M Rands, Stephen Meader, Chris P Ponting, Gerton Lunter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-07-01
Colecção:PLoS Genetics
Acesso em linha:https://doi.org/10.1371/journal.pgen.1004525
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