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8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineage.

Ten years on from the finishing of the human reference genome sequence, it remains unclear what fraction of the human genome confers function, where this sequence resides, and how much is shared with other mammalian species. When addressing these questions, functional sequence has often been equated...

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Main Authors: Chris M Rands, Stephen Meader, Chris P Ponting, Gerton Lunter
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2014-07-01
叢編:PLoS Genetics
在線閱讀:https://doi.org/10.1371/journal.pgen.1004525
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