Vascular dysfunction caused by loss of Brn-3b/POU4F2 transcription factor in aortic vascular smooth muscle cells is linked to deregulation of calcium signalling pathways

Abstract Phenotypic and functional changes in vascular smooth muscle cells (VSMCs) contribute significantly to cardiovascular diseases (CVD) but factors driving early adverse vascular changes are poorly understood. We report on novel and important roles for the Brn-3b/POU4F2 (Brn-3b) transcription f...

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Hlavní autoři:	Vaishaali Yogendran, Laura Mele, Oleksandra Prysyazhna, Vishwanie S. Budhram-Mahadeo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2023-11-01
Edice:	Cell Death and Disease
On-line přístup:	https://doi.org/10.1038/s41419-023-06306-w
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