Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

ABSTRACT Non‐NF2 Schwannomatosis (SWN) is a genetic disorder characterized by multiple non‐malignant schwannomas growing on the spine and peripheral nerves. Patients with SWN overwhelmingly present with intractable chronic pain. There are no FDA‐approved drugs to halt tumor growth or alleviate pain....

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2026-05-01
Цуврал:	Advanced Science
Нөхцлүүд:	anti‐IL‐6 EGF‐R inhibitor pain patient‐derived orthotopic model Schwannoma‐neuron‐macrophage cross talk schwannomatosis
Онлайн хандалт:	https://doi.org/10.1002/advs.202515597
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!