Assessing oxime reactivation efficacy using principal component analysis: Insights from nerve agents inhibited human butyrylcholinesterase
Background and purpose: The toxicity of organophosphorus compounds (OPs) and related nerve agents (NAs) impairs the cholinergic system via irreversible inhibition of acetylcholinesterase (AChE) activity by phosphylation of the catalytic serine. Reactivation of the enzyme activity largely depends on...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Association of Physical Chemists (IAPC)
2026-05-01
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| coleção: | ADMET and DMPK |
| Assuntos: | |
| Acesso em linha: | https://pub.iapchem.org/ojs/index.php/admet/article/view/3361 |
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