Cholesterol Oxime Olesoxime Assessed as a Potential Ligand of Human Cholinesterases

Olesoxime, a cholesterol derivative with an oxime group, possesses the ability to cross the blood–brain barrier, and has demonstrated excellent safety and tolerability properties in clinical research. These characteristics indicate it may serve as a centrally active ligand of acetylcholinesterase (A...

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Autores principales:	Dora Kolić, Goran Šinko, Ludovic Jean, Mourad Chioua, José Dias, José Marco-Contelles, Zrinka Kovarik
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2024-05-01
Colección:	Biomolecules
Materias:	reactivation organophosphate poisoning warfare nerve agent neuroprotection neurodegeneration
Acceso en línea:	https://www.mdpi.com/2218-273X/14/5/588
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