MLN4924 inhibits macrophage foam cell formation by enhancing autophagy and regulating metabolic phenotype
Abstract Background MLN4924 is a novel small molecule inhibitor of neddylation. During clinical trials, it has demonstrated promising therapeutic efficacy in hematological malignancies, lung cancer, and colon cancer. MLN4924 possesses anti-inflammatory properties and promotes cardiomyocyte autophagy...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BMC
2025-10-01
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| Sarja: | Lipids in Health and Disease |
| Aiheet: | |
| Linkit: | https://doi.org/10.1186/s12944-025-02683-7 |
| Tagit: |
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